While most organizations recognize the potential of process mining and plan to start process mining initia- tives, significant challenges for applying process mining in organizations remain unsolved. In this paper, we investigate the utility of process mining in organizations. Although process mining papers in the current Information Systems (IS) knowledge base deal with developed artifacts based on real-world scenarios, they often do not adequately reflect on their results’ utility and effectiveness in the application context, diminish- ing their contributions’ practical and theoretical implications. By discussing the results from the systematic literature review in the backdrop to the existing knowledge base, we develop four strategic guidelines for conducting process mining research with high relevance and managerial impact. Fellow researchers can follow these guidelines to rigorously plan, execute, and evaluate process mining research projects to gener- ate business value and achieve maximum organizational impact.